GEO DataSets

(Submitter supplied) A total of 116 patients, 96 with treatment-naïve unresectable hepatocellular carcinoma (uHCC) and 20 chronic liver disease without any cancer, were analysed for 17 cytokines and chemokines from serum and analysed for oncological features.

Organism:

Homo sapiens

Type:

Protein profiling by protein array

Platform:

GPL34302

116 Samples

Download data: TXT

(Submitter supplied) DDX39 and DDX56 recombinant proteins were assayed using commercial protein microarrays in order to detect potential interaction partners.

Organism:

Homo sapiens

Type:

Protein profiling by protein array

Platform:

GPL27459

3 Samples

Download data: GPR

(Submitter supplied) We measued IgG autoantibodies associated with Connective Tissue Diseases (CTDs) and Anti-Cytokine Antibodies (ACA) in SLE and healthy controls who received the BNT162b2 vaccine.

Organism:

Escherichia coli; Spodoptera frugiperda; Bos taurus; Homo sapiens; Sus scrofa; Triticum aestivum; Capra hircus

Type:

Protein profiling by protein array

Platform:

GPL34257

102 Samples

Download data: TXT, XLSX

(Submitter supplied) We measued IgG autoantibodies associated with Connective Tissue Diseases (CTDs) and Anti-Cytokine Antibodies (ACA) in SLE and healthy controls who received the BNT162b2 vaccine.

Organism:

Homo sapiens; Escherichia coli

Type:

Protein profiling by protein array

Platform:

GPL34255

113 Samples

Download data: TXT, XLSX

(Submitter supplied) The autoantibodies in serum (IgG antibody labeled with Cy3 and IgM antibody labeled with Cy5) were quantified by serum incubation human protein microarray, and the data of normal people and lung cancer patients were compared to find the predictive markers of autoantibodies in lung cancer

Organism:

Homo sapiens

Type:

Protein profiling by protein array

Platforms:

GPL29809 GPL29810

196 Samples

Download data: GPR

(Submitter supplied) Antibody recognition of Trypanosoma cruzi conserved proteins was assessed by evaluating pools of patient IgG samples on microarrays of 400,000 peptides covering these proteins as 15-mers with an overlap of 13 amino acids.

Organism:

Homo sapiens; Trypanosoma cruzi

Type:

Protein profiling by protein array

Platform:

GPL33498

3 Samples

Download data: TXT

(Submitter supplied) We analyzed if LCN2 modulates the activity of phosphotyrosine kinases in LPS/IFNg-stimulated primary murine macrophages (BMDMs)

Organism:

Mus musculus

Type:

Protein profiling by protein array

Platform:

GPL33127

10 Samples

Download data: TXT, XLSX

(Submitter supplied) To evaluate the short-term effect of elastase inhibition using telaprevir or sivelestat or DMSO on human islets

Organism:

Homo sapiens

Type:

Protein profiling by protein array

Platform:

GPL26730

24 Samples

Download data: XLSX

(Submitter supplied) Immune checkpoint inhibitors (ICIs) targeting PD-1/L1 have modest efficacy in hepatocellular carcinoma (HCC) as single agents, but combination regimens have demonstrated increased clinical benefit at the expense of treatment toxicities. Exposed phosphatidylserine suppresses the innate immune response in the tumor microenvironment (TME). Targeting phosphatidylserine does not induce tumor responses in the clinical setting when used as monotherapy or in combination with cytotoxic and targeted therapies, but may induce pro-inflammatory and –immune stimulating effects that enhance ICI activity. more...

Organism:

Homo sapiens

Type:

Protein profiling by protein array

Platform:

GPL33726

251 Samples

Download data: PNG, TXT

(Submitter supplied) Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling disorder that may occur following an infection, yet the clinical phenotype is poorly defined, the pathophysiology is unknown, and no disease-modifying treatments are available. We used rigorous criteria to recruit a cohort of post-infectious ME/CFS (PI-ME/CFS) volunteers (n=17) with matched healthy controls (n=21) to conduct deep clinical and biological phenotyping using an extensive battery of tests. more...

Organism:

Homo sapiens

Type:

Protein profiling by protein array

Platform:

GPL28516

42 Samples

Download data: TXT

(Submitter supplied) In this experiment, we studied the effect of ICANS on microglial kinase signaling

Organism:

Mus musculus

Type:

Protein profiling by protein array

Platform:

GPL33157

9 Samples

Download data: TXT

(Submitter supplied) To elucidate the molecular mechanism of MOTS-c against NASH progression, we screened for potential MOTS-c binding proteins using biotin-labeled MOTS-c and HuProt human proteome microarray.

Organism:

Homo sapiens

Type:

Protein profiling by protein array

Platform:

GPL33690

1 Sample

Download data: GPR

(Submitter supplied) Recent clinical studies have suggested that the risk of developing hepatocellular carcinoma might be lower in chronic hepatitis B (CHB) patients receiving tenofovir disoproxil fumarate (TDF) than in patients receiving entecavir (ETV), although there is no difference in biochemical and virological remission between two drugs. The effects of nucleoside analogs (NsAs; lamivudine and ETV) or nucleotide analogs (NtAs; adefovir disoproxil [ADV], TDF, and tenofovir alafenamide [TAF]) on cell growth and the expression of growth signaling molecules were investigated. more...

Organism:

Homo sapiens

Type:

Protein profiling by protein array

Platform:

GPL34000

8 Samples

Download data: TXT

(Submitter supplied) Influenza A virus (FLUAV) poses a significant threat to both humans and animals. While vaccination serves as the primary defense against influenza, the effectiveness of currently approved vaccines is suboptimal. To address this issue, we have developed modified live virus (MLV) vaccines against influenza using genome rearrangement techniques targeting the internal gene segments of FLUAV. The rearranged M2 (RAM) strategy involves cloning the M2 ORF downstream of the PB1 ORF in segment 2 and incorporating multiple early stop codons within the M2 ORF in segment 7. more...

Organism:

Mus musculus; Influenza A virus

Type:

Protein profiling by protein array

Platform:

GPL30424

112 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Macaca fascicularis; Homo sapiens; synthetic construct

Type:

Protein profiling by protein array; Other

Platforms:

GPL30414 GPL33775 GPL27885

1258 Samples

Download data

(Submitter supplied) Increasing evidence supports a role ofthat antibodies in thecan defense protect against active tuberculosis (TB) but knowledge of potentially protective antigens, especially at in the mucosal airways level, is limited. The main objective of this study was to identify antigen-specific airway and systemic immunoglobulin isotype responses that were associated with the outcome of controlled latent Mycobacterium tuberculosis (Mtb) infection (LTBI) compared to uncontrolled infection (TB) in nonhuman primates. more...

Organism:

Macaca fascicularis; synthetic construct

Type:

Protein profiling by protein array

Platform:

GPL30414

270 Samples

Download data: XLSX

(Submitter supplied) Increasing evidence supports a role ofthat antibodies in thecan defense protect against active tuberculosis (TB) but knowledge of potentially protective antigens, especially at in the mucosal airways level, is limited. The main objective of this study was to identify antigen-specific airway and systemic immunoglobulin isotype responses that were associated with the outcome of controlled latent Mycobacterium tuberculosis (Mtb) infection (LTBI) compared to uncontrolled infection (TB) in nonhuman primates. more...

Organism:

Macaca fascicularis; synthetic construct

Type:

Protein profiling by protein array

Platform:

GPL30414

270 Samples

Download data: XLSX

(Submitter supplied) Increasing evidence supports a role ofthat antibodies in thecan defense protect against active tuberculosis (TB) but knowledge of potentially protective antigens, especially at in the mucosal airways level, is limited. The main objective of this study was to identify antigen-specific airway and systemic immunoglobulin isotype responses that were associated with the outcome of controlled latent Mycobacterium tuberculosis (Mtb) infection (LTBI) compared to uncontrolled infection (TB) in nonhuman primates. more...

Organism:

Homo sapiens; Macaca fascicularis

Type:

Protein profiling by protein array

Platform:

GPL27885

196 Samples

Download data: XLSX

(Submitter supplied) Clinical heterogeneity of hepatocellular carcinoma (HCC) reflected in unequal outcome of treatment is poorly defined in molecular level, and molecular subtypes and their associated biomarkers have not been established to improve prognostification and treatment of HCC. Using reverse phase protein arrays (RPPA) technologies, we analyzed protein expression profiling data from HCC patients, uncovered mesenchymal subtype, and identified gene expression signature associated with mesenchymal phenotype of HCC.

Organism:

Homo sapiens

Type:

Protein profiling by protein array

Platform:

GPL32072

113 Samples

Download data

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Other; Protein profiling by protein array

Platform:

GPL33382

273 Samples

Download data: TXT